Advanced ageCardiovascular diseaseHypertensionDiabetes mellitusHigh cholesterolCigarette smokingRecreational drug useDepression or other psychiatric disordersPelvic surgery, including radical prostatectomy and colorectal surgeryPelvic radiation, such as for prostate cancer and some colorectal cancersTrauma to the pelvis (pelvic fracture), penis (penile fracture), and perineum
In addition, hormones and other substances determine how your nerves transmit ‘sexual signals’ and how blood vessels respond to the received signals. Arousing thoughts or nervous-system mechanisms such as touch reflexes are 2 ways you can get an erection.
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Oral phosphodiesterase type 5 inhibitors (PDE5 inhibitors) unless contraindicated are the recommended first line medical therapy for erectile dysfunction. Currently, there are four different PDE5 inhibitors available. They all work the same way and have essentially the same results. They differ in how long they last in your body and in side effects.
As with most other organ system in the human body, changes and loss of function is normal consequence of the ageing process. This is also true of the endocrine system, specifically the levels of testosterone production from the Leydig cells of the testicle. Accompanying the decrease in testosterone is a decrease in erections which also has a component in decrease in the blood supply to the penis making erection not as frequent and not as rigid compared with a young man’s erectile function. Although these changes are in itself not life threatening, they can impact a man’s relationship with his partner, and also ED may be a harbinger of other undiagnosed conditions such as coronary artery disease (CAD), hypercholesterolaemia or diabetes mellitus.6
Hormone imbalance, particularly low testosterone, can also play a role in ED. Men can naturally increase testosterone levels by routinely engaging in weight training exercises. For aging men whose testosterone levels have dipped, hormone therapy is a safe and effective treatment option.
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Treatments for erectile dysfunction are usually effective and the problem often goes away.
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Another placebo-controlled study showed that taking two 800 milligram tablets for two weeks improved erectile function in men with minimal erectile dysfunction. There’s also research that suggests using l-arginine in combination with l-glutamate and yohimbine hydrochloride is more effective than using l-arginine alone. (27)
Treatment of erectile dysfunction depends on the underlying cause of the condition. For fastest results, it’s best to consult a doctor to get appropriate treatment recommendations, which may include: 1. Lifestyle changes Maintaining a healthy weight Staying physically active (running, walking, stretching) Quitting smoking, excessive alcohol consumption and any drug abuse Stress management through meditation, sports, music, or yoga Getting adequate sleep and rest 2. Counseling
Response is dose related and usually occurs within 10–15 min, and does not require stimulation. The intraurethral preparation, medicated urethral suppository for erection (MUSE), consists of a tiny pellet of drug inserted into the urethral meatus. Response is also dose related, and onset similar to the cavernosal preparations.
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Therefore, men with these health conditions should not use vardenafil without having these conditions evaluated and stabilized first. For example, men with uncontrolled high blood pressure should have their blood pressure controlled; and men with potentially life-threatening abnormal heart rhythms should have these rhythms controlled.
Most effective form (Trimix) not covered by most insurance plans and may be quite expensive
Young adult men who frequently turn to pornography for stimulation, or who may even be struggling with a porn addiction, are much more likely to experience sexual dysfunctions in their lifetime.